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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZAP70 All Species: 35.15
Human Site: S520 Identified Species: 70.3
UniProt: P43403 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43403 NP_001070.2 619 69872 S520 F R K F S S R S D V W S Y G V
Chimpanzee Pan troglodytes XP_515637 619 69840 S520 F R K F S S R S D V W S Y G V
Rhesus Macaque Macaca mulatta XP_001101570 619 69877 S520 F R K F S S R S D V W S Y G V
Dog Lupus familis XP_861301 601 68596 Y512 Y A P E C I N Y Y K F S S K S
Cat Felis silvestris
Mouse Mus musculus P43404 618 70040 S519 F R K F S S R S D V W S Y G V
Rat Rattus norvegicus Q64725 629 71510 Y540 Y A P E C I N Y F K F S S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515271 507 56102 G423 M M D E V E L G S G N F G C V
Chicken Gallus gallus Q07494 984 109166 S805 Y R K F T S A S D V W S Y G I
Frog Xenopus laevis Q91736 902 100832 S723 Y R K F T S A S D V W S Y G I
Zebra Danio Brachydanio rerio O13146 981 109636 S810 Y R K F T S A S D V W S Y G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24145 939 104255 S848 L G I F S H A S D V W S F G V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189062 746 84636 S654 K F K F S S K S D V W S Y G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 53.6 N.A. 93.5 53.7 N.A. 57.6 22.6 24.2 25.2 N.A. 25.1 N.A. N.A. 34
Protein Similarity: 100 100 98.3 70.4 N.A. 96.1 70.9 N.A. 62.6 35.5 39.1 37.4 N.A. 40.8 N.A. N.A. 49.4
P-Site Identity: 100 100 100 6.6 N.A. 100 6.6 N.A. 6.6 73.3 73.3 73.3 N.A. 60 N.A. N.A. 80
P-Site Similarity: 100 100 100 20 N.A. 100 20 N.A. 6.6 93.3 93.3 93.3 N.A. 66.6 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 0 34 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 17 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 9 0 0 0 0 0 75 0 0 0 0 0 0 % D
% Glu: 0 0 0 25 0 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 34 9 0 75 0 0 0 0 9 0 17 9 9 0 0 % F
% Gly: 0 9 0 0 0 0 0 9 0 9 0 0 9 75 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 17 0 0 0 0 0 0 0 0 25 % I
% Lys: 9 0 67 0 0 0 9 0 0 17 0 0 0 17 0 % K
% Leu: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % L
% Met: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 17 0 0 0 9 0 0 0 0 % N
% Pro: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 59 0 0 0 0 34 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 50 67 0 75 9 0 0 92 17 0 17 % S
% Thr: 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 75 0 0 0 0 59 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % W
% Tyr: 42 0 0 0 0 0 0 17 9 0 0 0 67 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _